The Philadelphia 76ers were embarrassed at home in a back-to-back loss against the Cleveland Cavaliers on Wednesday, but they will have a chance to respond in Friday’s game in Philly.
Tyrese Maxey is still one of the NBA’s leading scorers, and my Cavaliers vs. The 76ers need a strong rebounder after his quiet game earlier in the week.
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Here are my free NBA picks for Friday’s Eastern Conference game at Xfinity Mobile Arena on Friday, January 16.
Cavaliers vs 76ers prediction
Cavaliers vs 76ers is the best bet: Tyrese Maxey Over 25.5 points (-120)
Tyrese Maxey is averaging a career-high 30.5 points per game this season, and tonight’s scoring line is set at a sweet 25.5 points. He finished with just 14 points on 5-of-16 shooting in Wednesday’s win, but posted 26+ in three straight games and nine of 10 before that.
Maxey has scored at least 26 in 29 of 37 games overall, including 13 of 19 at home. He has reached the Over in this goal line in 78.3% of his games, which means the odds here should be -360. I’ll happily take a discount here.
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Maxey’s 14 points in his last game outing represented his three-lowest of the season. He scored 27 in his other game with the Cleveland Cavaliers this season, and had 27 and 29 in two games with the Cavs last season.
Cleveland will be without Darius Garland and Sam Merrill tonight, and the Philadelphia 76ers should be close to full strength. I expect a very competitive show and a great performance from the Sixers’ electric leading scorer.
Cavaliers vs 76ers for the same game
Jaylon Tyson has finished with 20, 17, and 27 PRA in 25.3 minutes in his last three games. He started Wednesday in place of Sam Merrill, who was injured in that contest.
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Merrill and Darius Garland are both out tonight, which should mean another start for Tyson. He has averaged 21 PRAs out of 22, hitting the Over in the streak 13 times, including five of eight on the road.
The 76ers have hit the Over in nine of 13 games as a home favorite. Cleveland is 11-7 to Over on the road.
The teams have won 9-1 in the Over in their last 10 games.
Cavaliers vs 76ers SGP
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Tyrese Maxey Over 25.5 points
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Jaylon Tyson Over 21.5 points + rebounds + assists
Our SGP “from the city”: Spida Web
Donovan Mitchell has scored at least 31 points in nine of 16 road games this season, and dropped 35 and 46 points against the 76ers.
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Cavaliers vs 76ers SGP
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Tyrese Maxey Over 25.5 points
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Jaylon Tyson Over 21.5 points + rebounds + assists
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Donovan Mitchell Over 30.5 points
Cavaliers vs 76ers odds
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Spread: Cleveland +1.5 (-105) | Philadelphia -1.5 (-115)
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Moneyline: Cleveland +110 | Philadelphia -130
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Above/Below: Over 235 (-110) | Under 235 (-110)
Cavaliers vs 76ers betting trend you should know
The Cavaliers have hit a 1Q Over in 29 of their last 45 road games (+11.35 Units / 22% ROI). Find more NBA betting tips for Cavaliers vs. 76ers.
How to watch Cavaliers vs 76ers
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Location |
Xfinity Mobile Arena, Philadelphia, PA |
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The day |
Friday, January 16, 2026 |
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Tip |
7:00 pm ET |
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The TV |
ESPN |
Cavaliers vs 76ers latest injury
Not intended for use in MA.
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